BDBM50298192 CHEMBL561407::N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-methyl-6-oxohexyl)-N-isopropyl-4-methoxy-3-(4-methoxybutyl)benzamide

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)CN(C(C)C)C(=O)c1ccc(OC)c(CCCCOC)c1

InChI Key InChIKey=VJOSOVQVENJMHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298192   

TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298192(N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298192(N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-m...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298192(N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed