BDBM50298194 CHEMBL561141::methyl 5-(((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-methyl-6-oxohexyl)(isopropyl)carbamoyl)-2-methoxybenzylcarbamate

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)CN(C(C)C)C(=O)c1ccc(OC)c(CNC(=O)OC)c1

InChI Key InChIKey=BPPJAUKVTMVYPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298194   

TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298194(methyl 5-(((2S,3S,5R)-2-amino-6-(butylamino)-3-hyd...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298194(methyl 5-(((2S,3S,5R)-2-amino-6-(butylamino)-3-hyd...)
Affinity DataIC50: 3nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298194(methyl 5-(((2S,3S,5R)-2-amino-6-(butylamino)-3-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed