BDBM50298200 CHEMBL550005::N-((2S,3S,5S)-2-amino-5-(butylcarbamoyl)-3-hydroxy-6-methylheptyl)-4-ethyl-N-isopropyl-3-(3-methoxypropoxy)benzamide

SMILES CCCCNC(=O)[C@@H](C[C@H](O)[C@@H](N)CN(C(C)C)C(=O)c1ccc(CC)c(OCCCOC)c1)C(C)C

InChI Key InChIKey=NGPMIGMGKFRAJT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298200   

TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298200(N-((2S,3S,5S)-2-amino-5-(butylcarbamoyl)-3-hydroxy...)
Affinity DataIC50: 1nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298200(N-((2S,3S,5S)-2-amino-5-(butylcarbamoyl)-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298200(N-((2S,3S,5S)-2-amino-5-(butylcarbamoyl)-3-hydroxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed