BDBM50298237 1,2-Bis-(4-hydroxy-phenyl)-ethane::4,4'-(ethane-1,2-diyl)diphenol::CHEMBL577241

SMILES Oc1ccc(CCc2ccc(O)cc2)cc1

InChI Key InChIKey=URFNSYWAGGETFK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298237   

TargetEstrogen receptor beta(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50298237(1,2-Bis-(4-hydroxy-phenyl)-ethane | 4,4'-(ethane-1...)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at human ERbeta receptor expressed in HEK293T cells transfected with pGL4.27-(ERE)3-Luc assessed as transcriptional activation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50298237(1,2-Bis-(4-hydroxy-phenyl)-ethane | 4,4'-(ethane-1...)
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at ERbeta expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50298237(1,2-Bis-(4-hydroxy-phenyl)-ethane | 4,4'-(ethane-1...)
Affinity DataEC50:  75.1nMAssay Description:Agonist activity at ERalpha expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed