BDBM50298425 (2R,6S)-1-(4-chlorophenylsulfonyl)-2,6-dimethylpiperidine::1-(4-chloro benzene)-sulfonyl-cis-2,6-dimethylpiperidine::CHEMBL573102::rac-(cis)-1-(4-chlorophenylsulfonyl)-2,6-dimethylpiperidine

SMILES C[C@H]1CCC[C@@H](C)N1S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=HIWROFGCKQGFKO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298425   

TargetAcetylcholinesterase(Rat)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50298425(rac-(cis)-1-(4-chlorophenylsulfonyl)-2,6-dimethylp...)
Affinity DataIC50: 325nMAssay Description:Inhibition of Wistar rat brain homogenate AChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50298425(rac-(cis)-1-(4-chlorophenylsulfonyl)-2,6-dimethylp...)
Affinity DataIC50: 318nMAssay Description:Inhibition of human serum AChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Mysore

Curated by ChEMBL
LigandPNGBDBM50298425(rac-(cis)-1-(4-chlorophenylsulfonyl)-2,6-dimethylp...)
Affinity DataIC50: 312nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50298425(rac-(cis)-1-(4-chlorophenylsulfonyl)-2,6-dimethylp...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of gamma-secretase-mediated APP cleavage in human IMR-32 cells assessed as amyloid beta40 level after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed