BDBM50299220 8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-imidazo-[2,1-f]purine-2,4(3H,8H)-dione::CHEMBL575335

SMILES COc1ccccc1-n1c(cn2c1nc1n(C)c(=O)[nH]c(=O)c21)-c1cccc(O)c1

InChI Key InChIKey=XGJQUHDUEPMZTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299220   

TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50: 213nMAssay Description:Inhibition of EphB4 by [gamma33-P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM50299220(8-(2-Methoxyphenyl)-1-methyl-7-m-hydroxyphenyl-1H-...)
Affinity DataIC50: 368nMAssay Description:Inhibition of EphB4 assessed as blockade of synthetic substrate phosphorylation by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed