BDBM50299275 4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(piperidin-3-ylmethyl)benzamide hydrochloride::CHEMBL567174

SMILES Nc1ncc(nc1Oc1ccc2cc[nH]c2c1)-c1ccc(cc1)C(=O)NCC1CCCNC1

InChI Key InChIKey=HHUFICWXHSFBHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299275   

TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299275(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299275(4-(6-(1H-indol-6-yloxy)-5-aminopyrazin-2-yl)-N-(pi...)
Affinity DataIC50: 7.09E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed