BDBM50299276 4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin-2-yl)-N-(piperidin-3-ylmethyl)benzamide hydrochloride::CHEMBL567391

SMILES CC(Oc1nc(cnc1N)-c1ccc(cc1)C(=O)NCC1CCCNC1)c1c(Cl)cccc1Cl

InChI Key InChIKey=ZAIOSQVVOKXAEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299276   

TargetSerine/threonine-protein kinase Chk2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299276(4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant CHK2 by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50299276(4-(5-amino-6-(1-(2,6-dichlorophenyl)ethoxy)pyrazin...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant MET by [gamma-33P]ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed