BDBM50299557 (S)-2-((S)-2-((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)-3-phenylpropanamido)-3-phenylpropanoic acid::CHEMBL555206::H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI Key InChIKey=SZIMPGYQGJRODH-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50299557   

TargetMu-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataIC50: 769nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as effect on muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi:  0.248nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi:  0.248nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U69-593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Clinical Research Institute of Montreal

Curated by ChEMBL
LigandPNGBDBM50299557(H-2',6'-dimethyltyrosine-Tic-Phe-Phe-OH | (S)-2-((...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed