BDBM50299695 4-(4-Ethoxyphenyl)-2-imino-6-(thiophen-3-yl)-1,2-dihydropyridine-3-carbonitrile::CHEMBL572789

SMILES CCOc1ccc(cc1)-c1cc(nc(N)c1C#N)-c1ccsc1

InChI Key InChIKey=WZCMWVDGUSMHBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299695   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50299695(4-(4-Ethoxyphenyl)-2-imino-6-(thiophen-3-yl)-1,2-d...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human recombinant PDE3A by fluorescence polarization assay using cGMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50299695(4-(4-Ethoxyphenyl)-2-imino-6-(thiophen-3-yl)-1,2-d...)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of human recombinant PDE3A by fluorescence polarization assay using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed