BDBM50299727 CHEMBL574175::N-Cyclopropylmethyl-14beta-[3'-(4''-chlorophenyl)-propargylamino]-7,8-dihydronormorphinone

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NCC#Cc1ccc(Cl)cc1

InChI Key InChIKey=AJQMWPWKTSOHEA-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299727   

TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299727(N-Cyclopropylmethyl-14beta-[3'-(4''-chlorophenyl)-...)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299727(N-Cyclopropylmethyl-14beta-[3'-(4''-chlorophenyl)-...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299727(N-Cyclopropylmethyl-14beta-[3'-(4''-chlorophenyl)-...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]DPDPE from human recombinant delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed