BDBM50299730 CHEMBL574397::N-Cyclopropylmethyl-14beta-[4'-chlorophenylpropioloylamino]-7,8-dihydronormorphinone

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35NC(=O)C#Cc1ccc(Cl)cc1

InChI Key InChIKey=IHNDXKFQLVXZPN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299730   

TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299730(N-Cyclopropylmethyl-14beta-[4'-chlorophenylpropiol...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]U69593 from human recombinant kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299730(N-Cyclopropylmethyl-14beta-[4'-chlorophenylpropiol...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50299730(N-Cyclopropylmethyl-14beta-[4'-chlorophenylpropiol...)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]DPDPE from human recombinant delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed