BDBM50300073 (R)-ethyl 4-(6-(4-(3-ethylureido)phenyl)-4-(3-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate::CHEMBL567607

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOC[C@H]2C)c2cnn(C3CCN(CC3)C(=O)OCC)c2n1

InChI Key InChIKey=ZJGZMIKREDOSOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300073   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300073((R)-ethyl 4-(6-(4-(3-ethylureido)phenyl)-4-(3-meth...)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50300073((R)-ethyl 4-(6-(4-(3-ethylureido)phenyl)-4-(3-meth...)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed