BDBM50300090 CHEMBL576937::methyl 4-(6-(4-(3-ethylureido)phenyl)-4-(2-methylmorpholino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOC(C)C2)c2cnn(C3CCN(CC3)C(=O)OC)c2n1

InChI Key InChIKey=UPQRSQYXPGPCQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300090   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300090(methyl 4-(6-(4-(3-ethylureido)phenyl)-4-(2-methylm...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50300090(methyl 4-(6-(4-(3-ethylureido)phenyl)-4-(2-methylm...)
Affinity DataIC50: 721nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed