BDBM50300093 1-(4-(4-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea::CHEMBL576979

SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2C[C@H]3C[C@@H]2CO3)c2cnn(CC(F)(F)F)c2n1

InChI Key InChIKey=GBTSKWANNRXPIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300093   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300093(1-(4-(4-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5...)
Affinity DataIC50: 91nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50300093(1-(4-(4-((1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5...)
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed