BDBM50300094 CHEMBL573424::cis-1-(4-(4-(2,6-dimethylmorpholino)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl)phenyl)-3-methylurea

SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2C[C@H](C)O[C@H](C)C2)c2cnn(C3CCN(Cc4cccnc4)CC3)c2n1

InChI Key InChIKey=YLMYIJABZJMHCX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300094   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50300094(cis-1-(4-(4-(2,6-dimethylmorpholino)-1-(1-(pyridin...)
Affinity DataIC50: 84nMAssay Description:Inhibition of FLAG-tagged human mTOR by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
LigandPNGBDBM50300094(cis-1-(4-(4-(2,6-dimethylmorpholino)-1-(1-(pyridin...)
Affinity DataIC50: 3.88E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed