BDBM50300445 CHEMBL572545::N-hydroxy-10-methyl-9,10-dihydroacridine-9-carboxamide

SMILES CN1c2ccccc2C(C(=O)NO)c2ccccc12

InChI Key InChIKey=QZUGUUMWGJYJFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300445   

TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(N-hydroxy-10-methyl-9,10-dihydroacridine-9-carboxa...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(N-hydroxy-10-methyl-9,10-dihydroacridine-9-carboxa...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300445(N-hydroxy-10-methyl-9,10-dihydroacridine-9-carboxa...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed