BDBM50300448 CHEMBL585365::N-hydroxy-2,2-diphenylpropanamide

SMILES CC(C(=O)NO)(c1ccccc1)c1ccccc1

InChI Key InChIKey=LDAQHFMKFUATRE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300448   

TargetHistone deacetylase 5(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300448(N-hydroxy-2,2-diphenylpropanamide | CHEMBL585365)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC5 (620-1122) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300448(N-hydroxy-2,2-diphenylpropanamide | CHEMBL585365)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC4 (612-1034) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50300448(N-hydroxy-2,2-diphenylpropanamide | CHEMBL585365)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed