BDBM50300462 (2R,3'R,4'S,5'S,6'R)-6-chloro-5-(4-ethylbenzyl)-6'-(hydroxymethyl)-3',4',5',6'-tetrahydro-3H-spiro[benzofuran-2,2'-pyran]-3',4',5'-triol::CHEMBL577354

SMILES CCc1ccc(Cc2cc3C[C@]4(Oc3cc2Cl)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)cc1

InChI Key InChIKey=NFZPVCJATUZNDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300462   

TargetSodium/glucose cotransporter 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300462((2R,3'R,4'S,5'S,6'R)-6-chloro-5-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human SGLT2 expressed in HEK293.ETN cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50300462((2R,3'R,4'S,5'S,6'R)-6-chloro-5-(4-ethylbenzyl)-6'...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human SGLT1 expressed in african green monkey COS7 cells assessed as methyl-alpha-D-[U-14C]glucopyranoside uptake by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed