BDBM50300892 (E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)pyridin-2-yl)acrylamide::CHEMBL571142

SMILES COc1ccc(\C=C\C(=O)Nc2cc(ccn2)-c2c(noc2C(C)C)-c2ccc(F)cc2)c(OC)c1

InChI Key InChIKey=HSYSAQACEYOOEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300892   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300892((E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluoropheny...)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300892((E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluoropheny...)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant CK1delta kinase domain by Cherenkov countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Rat)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50300892((E)-3-(2,4-dimethoxyphenyl)-N-(4-(3-(4-fluoropheny...)
Affinity DataIC50: 47nMAssay Description:Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed