BDBM50302285 2,6-dimethoxy-4-(5-(2-morpholinopyrimidin-4-yl)furan-2-yl)phenol::CHEMBL567293

SMILES COc1cc(cc(OC)c1O)-c1ccc(o1)-c1ccnc(n1)N1CCOCC1

InChI Key InChIKey=HCRGRNXZXJGHHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302285   

TargetSerine/threonine-protein kinase mTOR(Human)
Kudos Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302285(2,6-dimethoxy-4-(5-(2-morpholinopyrimidin-4-yl)fur...)
Affinity DataIC50: 52nMAssay Description:Inhibition of mTOR kinase in human HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302285(2,6-dimethoxy-4-(5-(2-morpholinopyrimidin-4-yl)fur...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed