BDBM50302305 2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyridin-2-yl)butanamide::CHEMBL566248

SMILES CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C)cn1

InChI Key InChIKey=HMHCXYKWVOBPPR-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302305   

TargetCannabinoid receptor 2(Rat)
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at CB2 receptor in rat cerebellar membrane assessed as WIN-55212-2-stimulated [35S]GTPgammaS binding after 6 hrs by scintillation sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]CP55960 from human cloned CB2 receptor after 60 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]CP 55940 from human CB2 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]CP55960 from human cloned CB1 receptor after 120 mins by scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Adolor

Curated by ChEMBL
LigandPNGBDBM50302305(2,2-dimethyl-N-(5-methyl-4-(morpholinomethyl)pyrid...)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of [3H]CP 55940 from human CB1 receptor in cell free systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed