BDBM50302311 (S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)methanesulfonamide::CHEMBL567943

SMILES CS(=O)(=O)N(Cc1ccc2ccccc2c1)[C@H]1CCNC1

InChI Key InChIKey=MOEMPBAHOJKXBG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302311   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302311((S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)m...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302311((S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)m...)
Affinity DataIC50: 370nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302311((S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)m...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302311((S)-N-(naphthalen-2-ylmethyl)-N-(pyrrolidin-3-yl)m...)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed