BDBM50302314 CHEMBL578346::N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide

SMILES O=C(N(C1CCC1)C1CCNCC1)c1ccc2ccccc2c1

InChI Key InChIKey=AZTPZTRJVCAAMX-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50302314   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302314(N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide | CH...)
Affinity DataIC50: 10nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302314(N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide | CH...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302314(N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide | CH...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302314(N-cyclobutyl-N-(piperidin-4-yl)-2-naphthamide | CH...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed