BDBM50302315 (R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide::CHEMBL565639

SMILES CC(C)N([C@@H]1CCNC1)C(=O)c1ccc2ccccc2c1

InChI Key InChIKey=ZQHFQDYTXXQENI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302315   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302315((R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302315((R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide ...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302315((R)-N-isopropyl-N-(pyrrolidin-3-yl)-2-naphthamide ...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed