BDBM50302321 (S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide::CHEMBL567932

SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1ccc2ccccc2c1

InChI Key InChIKey=CEUJKSVEPJAVKD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302321   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302321((S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide |...)
Affinity DataIC50: 3nMAssay Description:Inhibition of serotonin reuptake at human serotonin transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302321((S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide |...)
Affinity DataIC50: 24nMAssay Description:Inhibition of noradrenaline reuptake at human noradrenaline transporter expressed in HEK293 cells after 15 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302321((S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide |...)
Affinity DataIC50: 744nMAssay Description:Inhibition of dopamine reuptake at human dopamine transporter expressed in HEK293 cells after 5 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed