BDBM50302371 1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,3-c]pyridin-4-yl]-1-morpholin-4-yl-methanone::CHEMBL567911

SMILES Cc1c[nH]c2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c12

InChI Key InChIKey=SFQQUBOFNDDLMP-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50302371   

TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human recombinant cannabinoid CB1 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50302371(1-[7-(3-Chloro-phenylamino)-3-methyl-1H-pyrrolo[2,...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human recombinant cannabinoid CB2 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed