BDBM50302391 1,7-dimethyl-1H-pyrazolo[3,4-b]quinolin-3-yl 2-phenoxyacetate::CHEMBL568574

SMILES Cc1ccc2cc3c(OC(=O)COc4ccccc4)nn(C)c3nc2c1

InChI Key InChIKey=PMSZFNMDLPXPCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302391   

LigandPNGBDBM50302391(1,7-dimethyl-1H-pyrazolo[3,4-b]quinolin-3-yl 2-phe...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of mouse recombinant PI3Kalpha expressed in baculovirus-infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302391(1,7-dimethyl-1H-pyrazolo[3,4-b]quinolin-3-yl 2-phe...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of recombinant PI3Kdelta expressed in baculovirus-infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
LigandPNGBDBM50302391(1,7-dimethyl-1H-pyrazolo[3,4-b]quinolin-3-yl 2-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PI3Kbeta expressed in baculovirus-infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed