BDBM50302544 (R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-c]-pyridin-3-yl)ethane-1,2-dione::CHEMBL583867

SMILES C[C@@H]1CN(CCN1C(=O)C(=O)c1c[nH]c2cnccc12)C(=O)c1ccccc1

InChI Key InChIKey=SXYMVJZFEUONDV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50302544   

TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using benzyloxy-4-(trifluoromethyl)coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 using 7-benzyloxyresorufin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50302544((R)-1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human ERG by channel flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed