BDBM50302621 (2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)phenyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol::CHEMBL577519

SMILES COC1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Sc2ccc(OC)cc2)c1

InChI Key InChIKey=YBYASAOVMRDJJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302621   

TargetSodium/glucose cotransporter 2(Mouse)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302621((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302621((2S,3R,4R,5S)-2-(4-Chloro-3-(4-methoxyphenylthio)p...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed