BDBM50302899 7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinolin-4-amine::CHEMBL566683

SMILES COc1ccc2c(NCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1

InChI Key InChIKey=XLJQUFRVZDFEAF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302899   

TargetHepatocyte growth factor receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302899(7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302899(7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4 in human liver microsomes preincubated with NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50302899(7-methoxy-N-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed