BDBM50302921 2-(N-tert-Butylamino)-3'-chloroheptanophenone::CHEMBL565382

SMILES CCCCCC(NC(C)(C)C)C(=O)c1cccc(Cl)c1

InChI Key InChIKey=OROOSQVGDDDAFY-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302921   

TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302921(2-(N-tert-Butylamino)-3'-chloroheptanophenone | CH...)
Affinity DataKi:  709nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302921(2-(N-tert-Butylamino)-3'-chloroheptanophenone | CH...)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302921(2-(N-tert-Butylamino)-3'-chloroheptanophenone | CH...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302921(2-(N-tert-Butylamino)-3'-chloroheptanophenone | CH...)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302921(2-(N-tert-Butylamino)-3'-chloroheptanophenone | CH...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed