BDBM50302932 1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one::CHEMBL566418

SMILES CC(NC1CCC1)C(=O)c1cccc(Cl)c1

InChI Key InChIKey=HKOVZQZDXNHYOJ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50302932   

TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataIC50: 86nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataIC50: 185nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataIC50: 258nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataKi:  343nMAssay Description:Displacement of [125I]RTI55 from cloned human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [125I]RTI55 from cloned human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50302932(1-(3-chlorophenyl)-2-(cyclobutylamino)propan-1-one...)
Affinity DataKi:  3.45E+3nMAssay Description:Displacement of [125I]RTI55 from cloned human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed