BDBM50303037 (1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine::CHEMBL570667

SMILES NCC1CCN(CC1)c1nccc(n1)-c1ccc2ccccc2c1

InChI Key InChIKey=QHLITPHIARVDJI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303037   

TargetDickkopf-related protein 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)
Affinity DataEC50:  630nMAssay Description:Inhibition of Dkk1-mediated Wnt/beta-casein signaling in osteosarcoma cells assessed as potentiation of TCF-luciferase responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50303037((1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed