BDBM50303170 CHEMBL579022::N-Acetyl-5-(N-difluoromethyl-1,2-dihydropyrid-2-one-4-yl)-2-carboxybenzenesulfonamide

SMILES CC(=O)NS(=O)(=O)c1cc(ccc1C(O)=O)-c1ccn(C(F)F)c(=O)c1

InChI Key InChIKey=DIRIVBQYONNWEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303170   

TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50303170(N-Acetyl-5-(N-difluoromethyl-1,2-dihydropyrid-2-on...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant COX-2 by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50303170(N-Acetyl-5-(N-difluoromethyl-1,2-dihydropyrid-2-on...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine COX-1 by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetLipoxygenase(Potato)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50303170(N-Acetyl-5-(N-difluoromethyl-1,2-dihydropyrid-2-on...)
Affinity DataIC50: 280nMAssay Description:Inhibition of potato 5-LOX after 5 mins by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed