BDBM50303352 CHEMBL4164057

SMILES COc1cc(CC(=O)NCc2ccc(cc2)C(=O)N2CCN(Cc3ccccc3-c3ccccc3)CC2)cc(OC)c1OC

InChI Key InChIKey=QAVBXJORAJZCMT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303352   

LigandPNGBDBM50303352(CHEMBL4164057)
Affinity DataKi:  180nMAssay Description:Inhibition of N-terminal 26 residues truncated 5-FAM labelled Bid-BH3 binding to MCL1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
LigandPNGBDBM50303352(CHEMBL4164057)
Affinity DataKi:  180nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from MCL1 (unknown origin) incubated for 2 hrs by fluorescence polarization-based competitive bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50303352(CHEMBL4164057)
Affinity DataKi:  180nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed