BDBM50303393 5-acetyl-2-(2-(4-ethylphenyl)-2-oxoethylthio)-4-(furan-2-yl)-6-methyl-1,4-dihydropyridine-3-carbonitrile::CHEMBL567130

SMILES CCc1ccc(cc1)C(=O)CSC1=NC(C)=C(C(C1C#N)c1ccco1)C(C)=O

InChI Key InChIKey=AFBHIYJIOBYRQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303393   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303393(5-acetyl-2-(2-(4-ethylphenyl)-2-oxoethylthio)-4-(f...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by Flexstation microplate spectrofluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303393(5-acetyl-2-(2-(4-ethylphenyl)-2-oxoethylthio)-4-(f...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain by quantitative high throughput screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed