BDBM50303410 4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5-triazine-2-carbonitrile::CHEMBL567785

SMILES Clc1cccc(Nc2nc(NC3CCCC3)nc(n2)C#N)c1

InChI Key InChIKey=QNUYHZAYXDMWMT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50303410   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain after 5 mins by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 79nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 851nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCaspase-6(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human Caspase 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCaspase-14(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of human Caspase 14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPapain(Papaya)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 513nMAssay Description:Inhibition of papaya papainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin Z(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303410(4-(3-chlorophenylamino)-6-(cyclopentylamino)-1,3,5...)
Affinity DataIC50: 6.46E+3nMAssay Description:Inhibition of human Cathepsin X/ZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed