BDBM50303441 9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-carbonitrile::CHEMBL567134

SMILES CCNc1nc(nc2n(cnc12)-c1cc(F)cc(F)c1)C#N

InChI Key InChIKey=VLZYXSQGILGQAI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50303441   

TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 251nMAssay Description:Inhibition of Trypanosoma cruzi cruzain after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetKallikrein-4(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 1.78E+5nMAssay Description:Inhibition of human Kallikrein 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCaspase-1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 7.08E+4nMAssay Description:Inhibition of human Caspase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 1(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 589nMAssay Description:Inhibition of human Cathepsin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetPapain(Papaya)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 33.1nMAssay Description:Inhibition of papaya papainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCathepsin Z(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303441(9-(3,5-Difluorophenyl)-6-(ethylamino)-9H-purine-2-...)
Affinity DataIC50: 316nMAssay Description:Inhibition of human Cathepsin X/ZMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed