BDBM50303570 (2-Oxatricyclo[3.3.1.13,7]dec-1-yl)-[1-(tetrahydropyran-4-ylmethyl)-1H-indol-3-yl]methanone::CHEMBL569992

SMILES O=C(c1cn(CC2CCOCC2)c2ccccc12)C12CC3CC(CC(C3)O1)C2

InChI Key

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303570   

TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303570((2-Oxatricyclo[3.3.1.13,7]dec-1-yl)-[1-(tetrahydro...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303570((2-Oxatricyclo[3.3.1.13,7]dec-1-yl)-[1-(tetrahydro...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50303570((2-Oxatricyclo[3.3.1.13,7]dec-1-yl)-[1-(tetrahydro...)
Affinity DataKi:  538nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed