BDBM50303661 4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Fluoro-3-methyl-1-naphthalen-2-ylmethyl-1H-indol-7-yl)acryloyl]amide::CHEMBL565799

SMILES Cc1cn(Cc2ccc3ccccc3c2)c2c(\C=C\C(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12

InChI Key InChIKey=HIZNWXUSWJBZEM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303661   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 360nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 3.65E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 8.82E+3nMAssay Description:Displacement of [3H]iloprost from human IP receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303661(4,5-Dichlorothiophene-2-sulfonic Acid[(E)-3-(5-Flu...)
Affinity DataIC50: 3.29E+4nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed