BDBM50303672 CHEMBL565604::Thiophene-2-sulfonic acid [2-(1-naphthalen-2-ylmethyl-2-oxo-1,2-dihydro-quinolin-8-yloxy)-acetyl]-amide

SMILES O=C(COc1cccc2ccc(=O)n(Cc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cccs1

InChI Key InChIKey=KYDJDYSPFRMLLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303672   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303672(Thiophene-2-sulfonic acid [2-(1-naphthalen-2-ylmet...)
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303672(Thiophene-2-sulfonic acid [2-(1-naphthalen-2-ylmet...)
Affinity DataIC50: 7.26E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed