BDBM50303675 2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yloxy)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acetamide::CHEMBL565992

SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2ncn(Cc3ccc(Cl)cc3Cl)c12

InChI Key InChIKey=GQXGWLGUUVXOJO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50303675   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 79nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 4.83E+3nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 5.88E+3nMAssay Description:Displacement of [3H]iloprost from human IP receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 7.96E+3nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303675(2-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-7-yl...)
Affinity DataIC50: 1.02E+4nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed