BDBM50303677 CHEMBL566016::N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(5-fluoro-3-methyl-7-(naphthalen-2-yloxy)-1H-indol-1-yl)propanamide

SMILES Cc1cn(CCC(=O)NS(=O)(=O)c2cc(Cl)c(Cl)s2)c2c(Oc3ccc4ccccc4c3)cc(F)cc12

InChI Key InChIKey=NWNFXHAFMZCAEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303677   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303677(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(5-fluoro-...)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303677(N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(5-fluoro-...)
Affinity DataIC50: 2.73E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed