BDBM50303686 CHEMBL584495::Thiophene-2-sulfonic Acid{(E)-3-[1-(4-Methoxybenzyl)-1Hindol-7-yl]acryloyl}amide

SMILES COc1ccc(Cn2ccc3cccc(\C=C\C(=O)NS(=O)(=O)c4cccs4)c23)cc1

InChI Key InChIKey=NCCPZKACUQIMIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50303686   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303686(Thiophene-2-sulfonic Acid{(E)-3-[1-(4-Methoxybenzy...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303686(Thiophene-2-sulfonic Acid{(E)-3-[1-(4-Methoxybenzy...)
Affinity DataIC50: 5.57E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed