BDBM50303695 CHEMBL585581::Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobenzyl)-1Hindol-7-y l]acryloyl}amide

SMILES Clc1ccc(Cn2ccc3cccc(\C=C\C(=O)NS(=O)(=O)c4cccs4)c23)c(Cl)c1

InChI Key InChIKey=UQEWWXSQAINMCT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50303695   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 60 mins repeated washing by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 357nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor after 1 hr by liquid scintillation counting in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 8.10E+3nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 8.18E+3nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50303695(Thiophene-2-sulfonic Acid{(E)-3-[1-(2,4-Dichlorobe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed