BDBM50304206 CHEMBL596059::N-(4-(benzo[d]thiazol-2-yl)-2-methoxyphenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES COc1cc(ccc1Nc1ncnc2cc(OC)c(OC)cc12)-c1nc2ccccc2s1

InChI Key InChIKey=HPJSNEQIUZAEBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304206   

TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304206(N-(4-(benzo[d]thiazol-2-yl)-2-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 63nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304206(N-(4-(benzo[d]thiazol-2-yl)-2-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304206(N-(4-(benzo[d]thiazol-2-yl)-2-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304206(N-(4-(benzo[d]thiazol-2-yl)-2-methoxyphenyl)-6,7-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed