BDBM50304207 CHEMBL595615::N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazolin-4-amine

SMILES COc1cc2c(Nc3ccc(cc3)-c3nc4ccccc4s3)ncnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=OZWMSXPIQVMFDE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50304207   

LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 54nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of VEGFR3 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304207(N-(4-(benzo[d]thiazol-2-yl)phenyl)-6-methoxy-7-(3-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PDGFRbeta by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed