BDBM50304212 CHEMBL593306::N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-methoxy-7'-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4'-amine

SMILES COc1ccc2nc(sc2c1)-c1ccc(Nc2ncnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)cc1

InChI Key InChIKey=MOQBNQNUPNPLCH-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50304212   

TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 48nMAssay Description:Inhibition of Aurora-B by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Aurora-A by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 130nMAssay Description:Inhibition of ERBB2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 200nMAssay Description:Inhibition of wild type EGF-R by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 390nMAssay Description:Inhibition of TIE2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 690nMAssay Description:Inhibition of VEGFR2 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR3 by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304212(N-[4-(Benzo[d]thiazol-2''-yl)-3-chlorophenyl]-6'-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbeta by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed