BDBM50304507 CHEMBL596562::N-Benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine

SMILES CN1CCN(CC1)c1cc(NCc2ccccc2)ncn1

InChI Key InChIKey=PEJDGFJXQFGUPP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304507   

TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304507(N-Benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-ami...)
Affinity DataKi:  207nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO cells after 90 mins by scintillation counting techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50304507(N-Benzyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-ami...)
Affinity DataKi:  417nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed